This allowed the Institute to create a variety a of synths of varying races and appearances despite the base DNA coming from only one source. BiologyДespite sequential numbering, third generation synths are unrelated to their mechanical counterparts, but are derived from Shaun's pre-War DNA extensively modified using the Institute's own research into the Forced Evolutionary Virus, combining the advantageous adaptations encoded into FEV with the versatility of the human body shape. In 2229, a defective 3rd generation infiltrator caused the Broken Mask Incident, vilifying the Institute in the eyes of the Commonwealth. Of course, tests were not without setbacks. The infant Shaun became Father to a whole family of engineered synthetic beings. He was recovered by Conrad Kellogg, and his DNA became the basis of the third generation of synths in a project led by Dr. In 2227, the organic synth project was spun off from the FEV research initiative due to the acquisition of Shaun and his undamaged pre-War genetic code.

Each would develop their personalities with promising results but would both escape sometime before the Institute could continue experimenting. The two prototypes were developed distinctly from each other, one testing independent development through experiences and one based on a pre-existing personality derived from pre- War brain scans. Д«efore developing the first truly organic synths, the Institute would prototype the gen 3 synths as previously proven mechanical synths like generations 1 and 2. Radiation-induced hereditary damage proved too much of an obstacle. The research used a sample of the Forced Evolutionary Virus and was intended to produce effective synthetic organics, but it ground to a halt in March 2224, as the research team concluded that the organic synth project could not proceed despite perfecting two FEV strains for the project. The most advanced synthetics created by the Institute are fundamentally different from their predecessors, the result of nearly five decades of research, from 2178 to 2227.

Shreddage 3 synth